Burning Fat and Building Bone by FSH Blockade

Sponton CH, Kajimura S.
Cell Metabolism
1Diabetes Center and Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA, USA 2Obesity and Comorbidities Research Center—OCRC, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil
The rise of follicle-stimulating hormone (FSH) is a hallmark of menopause associated with osteoporosis and visceral adiposity. In Nature, Zaidi and colleagues (Liu et al., 2017) report that blocking FSH action reduces body fat by promoting brown/beige fat thermogenesis, potentially providing a new intervention for the treatment of menopause-related metabolic diseases.
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